The Conference „uDay XVI - Assistive Technologies in Working Environ- ments“ addresses how digitization, virtualization and real-time processing affect working. Changes in skills are required and are sometimes higher in mental demands than previous sequential work processes. pose major challenges to the world of work, and especially to industrial production. At the same time, the same principles and technologies offer the opportunity of providing workers with all-round support for these new requirements. Science is able and required to identify the possibilites for assistance and develop as well as optimize solutions from a technological and process-ori- ented point of view. uDay XVI is dedicated to the present state-of-reserach and current solutions in the relevant research domains.